That's the Bad news, the Good news is that Central Defender Steve Blatherwick has recovered enough from illness to make the squad and is likely to start alongside Ian Evatt at the back.
The Spireites will go into the match in with full confidence behind them especially two goal striker T'cham N'toya it is likely that N'toya will start alongside Mark Debolla as was the case on saturday.
The other absentees are Mark Hudson, Kevin Dawson and Wayne Allison although Allison is due to be placed into the squad for saturday's game against Bradford City.
Chesterfield v Rotherham United is a fixture that most Spireites look forward to as the millers just can't beat us. 19 games and 25 years since Rotherham won and most millers are fearing that this run will continue, they have picked up just two goals this season and are hovering just above the relegation places at present. Reports are that the Millers are better than there league position at present.
Phil Gilchrist with an injury and Paul Shaw left out because he is on loan from Sheffield United and boss Neil Warnock doesn't want him cup tied are missing from there line up.