League Two leaders Chesterfield are without virus-hit defenders Dwayne Mattis, Ian Breckin and Jack Hunt.
Fellow defender Kelvin Lomax (ankle) will have a late fitness test, while midfielder Derek Niven serves the last of a three-match ban.
The two sides meet just a month after Paul Peschisolido's Burton won 2-1 at Chesterfield in the league.
Source: BBC Sport
Source: BBC Sport